计算成像是一个将计算算法与智能光学设计相结合的前沿领域，它能够从视觉数据中提取比传统成像方法更多的信息。该技术的目标在于克服传统2D成像的局限性，后者可能受到像差、噪声和曝光时间等物理因素的限制。然而，大多数计算成像技术仅适用于通用场景。我们提出的元成像传感器和宽视场波前传感器，能够在多种应用中实现多点像差估计和校正，而无需对光学前端进行任何额外的硬件改动。我们的方法为计算成像技术在遥感、天文观测、工业检测、自动驾驶和精准医疗等领域的应用开辟了新的道路。

代表性论文

• Aberration-robust monocular passive depth sensing using a meta-imaging camera, Light: Science & Applications 2024
  

• Direct Observation of Atmospheric Turbulence with a Video-rate Wide-field Wavefront Sensor, Nature Photonics 2024
  

• Two-photon synthetic aperture microscopy for minimally invasive fast 3D imaging of native subcellular behaviors in deep tissue, Cell 2023

• Virtual-scanning light-field microscopy for robust snapshot high-resolution volumetric imaging, Nature Methods 2023

• Real-time denoising enables high-sensitivity fluorescence time-lapse imaging beyond the shot-noise limit, Nature Biotechnology 2023

• Rationalized deep learning super-resolution microscopy for sustained live imaging of rapid subcellular processes, Nature Biotechnology 2023

• An integrated imaging sensor for aberration-corrected 3D photography, Nature 2022

• sA digital mask to safeguard patient privacy, Nature Medicine 2022

• Evaluation and development of deep neural networks for image super-resolution in optical microscopy, Nature methods 2021

• Iterative tomography with digital adaptive optics permits hour-long intravital observation of 3D subcellular dynamics at millisecond scale, Cell 2021

• Computational optical sectioning with an incoherent multiscale scattering model for light-field microscopy, Nature communications 2021

• A modular hierarchical array camera, Light: Science & Applications 2021

• Mirror-enhanced scanning light-field microscopy for long-term high-speed 3D imaging with isotropic resolution, Light: Science & Applications 2021

• DiLFM: an artifact-suppressed and noise-robust light-field microscopy through dictionary learning, Light: Science & Applications 2021

• Unsupervised content-preserving transformation for optical microscopy, Light: Science & Applications 2021

• Super-resolution imaging of fluorescent dipoles via polarized structured illumination microscopy, Nature communications 2019

• Video-rate imaging of biological dynamics at centimetre scale and micrometre resolution, Nature photonics 2019