Nature Methods | A new self-supervised denoising method to break the shot-noise limit in calcium ...
Calcium imaging allows parallel recording of neural activity in living organisms at single-cell resolution, offering great potential for unraveling the mechanisms of information propagation, integration, and computation in neural circuits. Achieving high signal-to-noise ratio (SNR) calcium imaging data is crucial for accurate neural function analysis. However, the low peak accumulation and rapi...
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