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Guihua Xiao

Assistant Researcher

BNRist, Tsinghua University


Research direction

Optoelectronic Neural Interface, Neural Modulation, Neural Representation

Education and Experience:

07/2022 – Present, Assistant Professor at BNRist, Tsinghua University

07/2020 – 07/2022, Postdoc. at Department of Automation, Tsinghua University

09/2014 – 07/2020, Ph.D. Bioelectronics, Aerospace Information Research Institute, Chinese Academy of Sciences

03/2018–03/2019, Visiting Scholar, Mechanical Engineering, University of Minnesota

09/2010 – 07/2014, Department of Measurement and Control Technology and Instrumentation, Beijing University of Chemical Technology

Representative Publications in past 3 years (# co-first author, *corresponding author):

1、Hao Xie#; Xiaofei Han#;Guihua Xiao#; Hanyun Xu; Yuanlong Zhang; Guoxun Zhang; Qingwei Li; Jing He; Dan Zhu; Xinguang Yu; Qionghai Dai*; Multifocal fluorescence video-rate imaging of centimetre-wide arbitrarily shaped brain surfaces at micrometric resolution,Nature Biomedical Engineering, 2023, 00(00): 00-00

2、Penghui Fan#; Rujin Zhang#;Guihua Xiao#; Yilin Song; Chaowei Zhuang; Lekang Yuan; Fan Mo; Botao Lu; Zhaojie Xu; Yiding Wang; Jinping Luo; Mixia Wang; Weidong Mi; Jiangbei Cao*; Qionghai Dai*; Xinxia Cai*; Simultaneous recording of neuronal discharge and calcium activity reveals claustrum-cortex neurosynchrony under anesthesia,Fundamental Research, 2024, 00(00): 00- 00

3、Chui Kong; Yangzhen Wang;Guihua Xiao*; Neuron populations across layer 2-6 in the mouse visual cortex exhibit different coding abilities in the awake mice,Frontiers in Cellular Neuroscience, 2023, 17: 01-11

4、Hanyun Xu#; Tingting Jin#; Rujin Zhang; Hao Xie; Chaowei Zhuang; Yanyang Zhang; Dongsheng Kong;Guihua Xiao*; Xinguang Yu*; Cerebral cortex and hippocampus neural interaction during vagus nerve stimulation under in vivo large-scale imaging,Frontiers in Neuroscience, 2023, 17: 01- 10

Research Focus:

My research is centered on advanced observation technologies and modeling methods for comprehensive brain function, with a particular emphasis on the development of brain-computer interface devices. I employ photoelectric joint detection and multimodal neural activity recording systems to monitor and analyze large-scale and high-resolution neural activities across different states of consciousness. This includes constructing extensive continuous brain activity monitoring systems in the cerebral cortex and developing multi-nuclear, multimodal detection techniques for deeper brain structures. I leverage photoelectric fusion detection and large-scale data analysis to investigate the neural dynamics and regulatory mechanisms underpinning the transitions between consciousness levels, such as during sleep and anesthesia. Furthermore, my work integrates photogenetic and electrical stimulation strategies to explore the subconscious changes and control patterns in these states. I also study neural representations and computational models under cognitive decision-making paradigms, focusing on the brain’s processing of visual and auditory information.

Honors & Awards:

2021 Committee member of Biomedical Imaging Technology, China Medical Biotechnology

2021 Cognitive Computation and Systems Editorial Board Member

2020 President's Scholarship of CAS

2020 Outstanding doctoral graduate in Beijing

英文名 职称 Assistant Researcher
院系 BNRist, Tsinghua University 邮箱 xiaoguihua@tsinghua.edu.cn
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