Introduction

David Kleinfeld received his Ph.D. from UCSD and was a Member of Technical Staff at the former AT&T Bell Laboratories prior to joining the faculty at UCSD. He is a recipient of a David and Lucile Packard Foundation Interdisciplinary Science Award, a NIH Directors Pioneer Award, a NINDS Research Program Award, and currently holds the Experimental Biophysics Endowed Chair through Physics. David is a fellow of the American Association for the Advancement of Science and a member of the American Academy of Arts and Sciences. He currently leads the Specialization on Computational Neuroscience through the Neurosciences Graduate Program.

Abstract

Neuronal activity is intimately linked with changes in metabolism and subsequent changes in regional blood flow. Even minor interruptions in flow can adversely effect cognitive function.
This seminar will introduce our explorations on the structure and neuronal control of blood flow in the brain, and variations and interruptions in that flow, at the level of brain-wide vascular networks down to that of individual microvessels.